Scientists Discover How Psychedelics Turn Memory Into Hallucinations
Summary
Recent research reveals that psychedelics may transform brain function by reducing external visual input while enhancing internal memory networks. These compounds primarily interact with serotonin receptors, particularly the 2A receptor, highlighting their potential impact on perception and reality construction.
Key Insights
What is the 5-HT2A receptor and why is it important for psychedelics?
The 5-HT2A receptor is a subtype of serotonin receptor in the brain that acts as the primary target for classic psychedelics like LSD and psilocybin, mediating their hallucinogenic effects by altering perception, cognition, and neuronal excitation.
Sources:
[1]
How do psychedelics potentially transform memory into hallucinations?
Psychedelics reduce external visual input while enhancing internal memory networks through 5-HT2A receptor activation, which promotes neuroplasticity and rewires neuronal networks, leading to hallucinations derived from internal memories rather than external stimuli.
Sources:
[1]